We routinely use Surgipath's O-fix on breast tissue for subsequent Her-2 testing via IHC and FISH. Is this now disallowed? According to the labeling, O-fix is a formalin based fixative with ethanol and acetic acid added. I would consider it an alcohol based fixative and disallowed only in the absence of the formalin. 
 
 
John P.J. Coleman HT(ASCP)QIHC
Clinical Specialist
Anatomic Pathology
Sentara Laboratory Services
Cell/Voicemail(757)335-2159
pager: (757)456-6695
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