RE: [Histonet] to do or not to do egfr

From:"Weems, Joyce"

Don't we need to be sure that the FDA approved reagents are used? If not apatient can be denied clinical trials. Joyce-----Original Message-----From: histonet-bounces@lists.utsouthwestern.edu[mailto:histonet-bounces@lists.utsouthwestern.edu]On Behalf Of Willis,DonnaSent: Thursday, March 11, 2004 9:57 AMTo: 'KHays@mbhs.org'; histonet@pathology.swmed.eduSubject: RE: [Histonet] to do or not to do egfrKathy,Just to let you know.  We have been using the DAKO Clone H11 on both theDako and Ventana instruments for a long time.  When we got a request from onof our Oncologist in Feb for EGFR on archived colon cases we thought noproblem.  We used the H11 clone and everything was negative.  The oncologistquestioned the clone we were using and asked us to get the new EGFR pharmDxclone 2-18C9 and retest the cases.  We did and they were positive.  Justbeware that if the patient is being tested for the Erbitux drug we all mighthave to use the 2-18C9 clone.Donna WillisHistology Lab ManagerHarris Methodist Fort Worth, Tx-----Original Message-----From: histonet-bounces@lists.utsouthwestern.edu[mailto:histonet-bounces@lists.utsouthwestern.edu]On Behalf OfKHays@mbhs.orgSent: Wednesday, March 10, 2004 4:33 PMTo: histonet@pathology.swmed.eduSubject: [Histonet] to do or not to do egfrKathy Tedford-Hays  HT (ASCP)Technical Specialist, Histology Dept(601)-968-3070 ext 7398Baptist Medical Center1225 North State StreetJackson, MS 39202we are currently getting several requests for the test egfr as many of you.  my questions are:  is this another immunostain or is this something more?we were told that if the patients are positive then they are candidates for a new chemotherapy for colon cancer.   if this is not another immunostain then what labs are doing the egfr  for this new chemo?  any information would be appreciated.  thank you.The information contained in this email is confidential and is intended forthe recipient only.  Do not forward this email without permission from itsoriginator._______________________________________________Histonet mailing listHistonet@lists.utsouthwestern.eduhttp://lists.utsouthwestern.edu/mailman/listinfo/histonetThe information contained in this message and any attachments is intendedonly for the use of the individual or entity to which it is addressed, andmay contain information that is PRIVILEGED, CONFIDENTIAL, and exempt fromdisclosure under applicable law.  If you are not the intended recipient, youare prohibited from copying, distributing, or using the information.  Pleasecontact the sender immediately by return e-mail and delete the originalmessage from your system._______________________________________________Histonet mailing listHistonet@lists.utsouthwestern.eduhttp://lists.utsouthwestern.edu/mailman/listinfo/histonetConfidentiality Notice ** The information contained in this message may be privileged and is confidential information intended for the use of the addressee listed above. If you are neither the intended recipient nor the employee or agent responsible for delivering this message to the intended recipient, you are hereby notified that any disclosure, copying, distribution or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this communication in error, please notify us immediately by replying to the message and deleting it from your computer.Thank you. Saint Josephs Health System, Inc.

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