RE: Burned Tissue?
Just a thought, but the fact that the outer cuts of the
biopsy look "burnt" suggest to me that the tissue is over dried. Possibly too
long in the dehydrating reagent you are using. Is this problem with biopsies
only or across varying tissue type and sizes?
been having a real problem this last week or so with tissue coming off my
Shandon Pathcentre looking "burned," according to my pathologist. What could
cause such an artifact? I thought maybe it was a paraffin temp problem, but
there's been no record of the processor going outside temp limits. Thought it
may be insufficient de-paraffinization (still hoping it's that). It doesn't
happen to everything, and the weirdest part is that one level from a biopsy
showed the artifact while deeper levels did not.
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