Picric Acid Fixatives - Self-Test.
From: | "Monson, Frederick C." |
Purely Rhetorical questions.
If you were asked to prepare a fixative that contained PICRIC ACID and any
of the following, what would you do?
chromic acid
copper salts
iron salts
dichromates
mercuric salts
sulfuric acid
osmic acid
platinic acid
silver salts
nitric acid
ammonium salts
metal hydroxides (sodium hydroxide?)
According to Gray's "Microtomist's Formulary and Guide", such were done by
many histologists prior to publication in the 1950's.
How would you 'REACT' if a bottle of picric acid arrived at your lab with a
metal cap.
Would you prepare Hollande's Fixative for your boss? Someone did somewhere,
and what was left ultimately exploded. Would you prepare it? Then what
would you do?
What IS the hazard of picric acid? So could you keep it safely in your lab?
How?
That's why we were required to take all those chem classes in the first
place.
Regards,
Frederick C. Monson, PhD
Center for Advanced Scientific Imaging
West Chester University
West Chester, Pennsylvania, USA, 19383
610-738-0437
fmonson@wcupa.edu
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