labeling of bone

From:Vicki Kalscheur <kalschev@svm.vetmed.wisc.edu>

     
     George Spurr-
     
     Acid methods of decalcification will destroy all fluorochrome labels 
     due to liberation of calcium from its ionic state through ionic 
     exchange, rendering a soluble calcium salt in the matrix. I am not 
     aware of any advances in paraffin processing that will preserve bone 
     labels. 
     
     Vicki Kalscheur




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