Re: Paraffin cleaning

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Xylene substitutes can cause problems for an instrument that's designed to 
remove xylene from paraffin.  The processors which do this (Leica first, then 
RMC/Ventana about a year later) were originally designed to remove xylene 
from paraffin, and they do this quite well.

The problem with xylene substitutes is that each compound has a different 
vapor pressure, and the conditions of temperature and vacuum which work great 
for xylene removal may not necessarily do the same for the substitutes.

I don't know what the answer is, outside of a *lot* of R&D from the 
manufacturers and maybe writing different cleaning programs depending on 
which substitute you are using.

Maybe the simplest thing to do is use xylene in the processor?


Bob Chiovetti

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