RE: Immuno Control Tissue/AFP

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From:Abizar Lakdawalla <>
To:"'Barnhart, Tammy'" <>,
Content-Type:text/plain; charset="iso-8859-1"

Alpha Fetoprotein is found in mammalian embryonic serum and in fetal liver
hepatoma, yolk sac, several germ cell tumor (form hyaline droplets), in most
non-seminomatous germ cell tumors, in endodermal sinus tumors, and in
regenerating hepatic parenchyma. So, any of these could serve as positive
controls. We sell hepatoma/hepatocellular carcinoma slides as positive


-----Original Message-----
From: Barnhart, Tammy []
Sent: Thursday, March 16, 2000 7:33 AM
Subject: Immuno Control Tissue

I need help locating control tissue for the Alpha Fetoprotein antibody.  I
would like to have a heptatocelluar carcinoma sample to use for a positive
control, but we rarely see those tumors.  We have had a couple of needle bxs
come through, but the sample size is insufficient to use as control
material.  Can anyone help? P.S.  We have never seen a yolk sac tumor!!!!

Tammy Barnhart, B.S., HTL(ASCP)
Anatomic Pathology Supervisor
St. Alexius Medical Center/ Pathology Consultants, P.C.
Bismarck, ND

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