Re: Thioflavin S

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From:Roger Moretz <>
To:Mike King <>,
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Thanks Mike.  I think that the actual published
article I was thinking of was the Wisniewski, et al
reference.  I had that confused with the original
Neuropath meeting presentation by Raul, and had
forgotten that he mysteriously disappeared from the
author list by the time the full paper made it into
the literature.  Due to upheavals in the lab, all of
my references are stuffed into boxes at home, and
retrieving things is purely serendipitous.  Part of
the results of all these years of flattening semithin
epoxy sections with chloroform and other nasty
chemicals seems to be an inability to get all those
neurons firing and making the right connections :). 
Or, it could just be another "Senior Moment".


--- Mike King <> wrote:
> LuAnn Anderson <> wrote:
> ... Has anyone out  there heard of a Thio S for
> amyloid?  
> Looking for the Rudelli ref. suggested by Roger
> Moretz, nothing showed up
> in PubMed (
> but these references
> might help if you have access to a medical library:
> Westermark GT, Johnson KH, Westermark P Methods
> Enzymol 1999;309:3-25
> Staining methods for identification of amyloid in
> tissue. 
> Kelenyi G Acta Neuropathol (Berl) 1967 Feb
> 3;7(4):336-48 Thioflavin S
> fluorescent and Congo red anisotropic stainings in
> the histologic
> demonstration of amyloid.  
> Yamamoto T, Hirano A.  A comparative study of
> modified Bielschowsky, Bodian
> and thioflavin S stains on Alzheimer's
> neurofibrillary tangles.
> Neuropathol Appl Neurobiol. 1986 Jan-Feb;12(1):3-9.
> Wisniewski HM, Wen GY, Kim KS.  Comparison of four
> staining methods on the
> detection of neuritic plaques. Acta Neuropathol
> (Berl). 1989;78(1):22-7.
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