Re: Zinc Formalin (formalin pigment)
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From: | "J. A. Kiernan" <jkiernan@julian.uwo.ca> |
To: | Gervaip@aol.com |
Reply-To: | |
Date: | Mon, 21 Jun 1999 00:04:05 -0400 (EDT) |
Content-Type: | TEXT/PLAIN; charset=US-ASCII |
On Sun, 20 Jun 1999 Gervaip@aol.com wrote:
> ... have been using zinc formalin for years now. It is wonderful for
> ... can rust metal lids on specimen jars and formalin pigments are
> present in the sections.
This is a very interesting observation, because plain acidic
formaldehyde solutions take quite a while to generate "formalin
pigment" from haemoglobin. You say that you use the fixative
in a processor, so presumably you are fixing for a short time
such as overnight or 24 hours. Is this so? If it is so, then there
is an implication that formalin pigment generation occurs more
rapidly in zinc formalin than in simple acidic or non-neutralized
formalin. This is something everyone should know about. Please
tell us more!
John A. Kiernan,
Department of Anatomy & Cell Biology,
The University of Western Ontario,
LONDON, Canada N6A 5C1
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