Re: paraldehyde and a substitute
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From: | Geoff McAuliffe <mcauliff@UMDNJ.EDU> |
To: | Gayle Callis <uvsgc@msu.oscs.montana.edu> |
Reply-To: | |
Date: | Fri, 04 Jun 1999 13:37:40 -0400 |
Content-Type: | text/plain; charset=us-ascii |
Gayle Callis wrote:
> Paraldehyde is a controlled substance, requiring an arm and a leg to
> purchase (my experience) with a DEA number to order. plus expense and then
> short shelf life.
> There is a substitute, acetaldehyde, non controlled, and done by wonderwoman
> Peggy Wenk. It was inJournal of Histotechnology 19 p 353, Dec 1996.
>
You can also consult "Staining Properties of Aldehyde Fuchsin analogs" by
Buehner, Nettleton and Longley. J. Histochem. Cytochem 27:782-787, 1979. They
explain why acetaldehyde works, why one has to use more acetaldehyde than
paraldehyde, and that n-butyraldehyde may be better than either of the other
aldehydes.
Geoff
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Neuroscience and Cell Biology
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