Re: paraldehyde and a substitute

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From:Geoff McAuliffe <mcauliff@UMDNJ.EDU>
To:Gayle Callis <>
Date:Fri, 04 Jun 1999 13:37:40 -0400
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Gayle Callis wrote:

> Paraldehyde is a controlled substance, requiring an arm and a leg to
> purchase (my experience) with a DEA number to order. plus expense and then
> short shelf life.
> There is a substitute, acetaldehyde, non controlled, and done by wonderwoman
> Peggy Wenk.  It was inJournal of Histotechnology 19 p 353, Dec 1996.

    You can also consult "Staining Properties of Aldehyde Fuchsin analogs" by
Buehner, Nettleton and Longley. J. Histochem. Cytochem 27:782-787, 1979. They
explain why acetaldehyde works, why one has to use more acetaldehyde than
paraldehyde, and that n-butyraldehyde may be  better than either of the other

Geoff McAuliffe, Ph.D.
Neuroscience and Cell Biology
Robert Wood Johnson Medical School
675 Hoes Lane, Piscataway, NJ 08854
voice: (732)-235-4583; fax: -4029

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