Heather:
  Have you consider checking the working condition of your microtome? Sometimes all those problems stem form a "need to adjust" microtome. We always used AccuEdge and never changed to any other brand even when we received free samples to "temp us".
  Hope this will help you!
  René J.

Heather.A.Harper@pcola.med.navy.mil wrote:
  Well I adjusted the angle like every one suggested, starting in
increments. I could not find one angle that Accu Edge blade would cut a
smooth section. Every time it was compressed with wrinkles. I tried the Dura
Edge and found an angle for that but only had one blade of that left and am
out of the edge right. Is Accu Edge this hard to get an angle where it cuts
right? I have an RM 2235 Leica microtome. All of a sudden cutting seems to
be a nightmare.



Heather A. Harper

Naval Hospital

Pensacola, FL 



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