[Histonet] High Profile Micrtome Blades


  I want to thank everybody who sent me their samples and left over high
profile blades. Now I have another dilemma. I'm having so much fun trying
out new blades. I want to know if anybody can help me trouble shoot this
problem in cutting. When I tried the Duraedge and Sturkey blades, I noticed,
one section would be thick, the next was thin. With the AccuEdge, it cut
nice except the ribbons were wrinkled and I had to stretched them out on the
water bath. It's almost as though the blade is too thick or I need something
adjusted on the knife holder. I cut at 5 degree angle and always have.
Anybody have any ideas on what to do here. I am not getting those nice
smooth wrinkle free ribbons. I'm concluding it's the blade holder needs
adjusting or maybe the angle. Any input would be great. Thanks again

P.S. This is a fairly new microtome. It's less than a year old.


Heather A. Harper

Histology Supervisor       

Naval Hospital

Pensacola, FL

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