Jackie

The Detroit Zoo is actually in Royal Oak, a very nice, and safe subdivision of Detroit.  (Detroit gets a really bad rap, you know?)

Good places to search for Hotels:

Troy, MI-- Awesome mall nearby, Somerset
Madison Heights- right off 14 Mile Rd there is a Fairfield Inn and some more shopping  at Oakland Mall - not as great as Somerset.
Novi- more great shopping and about 20/30 minutes from the Zoo.

Make sure they visit downtown Royal Oak - sort of eclectic, and downtown Birmingham- high end shopping.

Feel free to contact me personally,

Dawn Truscott
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