[Histonet] Sphingomyelin


Mary Lloyd and Dr Rosebush ask about sphingomyelin:
I am no expert on sphingomyelin (underlined!) but had to suffer through classes on the subject during histotechnology training in England. As a histotechnologist, when you think about sphingomyelin, you think about methods that will stain normal myelin like Sudan black, PAS and acid hematein.
In an excellent book edited by Isobel Filipe and Brian Lake "Histochemistry in Pathology" Churchill Livingstone (1983) there are several references to Neuman Pick disease and histochemical methods to demonstrate sphingomyelin, and cholesterol and gangliosides which can accompany the disease process.
Mike Titford
USA Pathology
Mobile AL USA
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