Re: Manganese Stain?

From:Roger Moretz

I don't know about staining manganese, but try a
PubMed search for WR Markesbery.  He has published a
lot about the possible colocalization of manganese
with Alzheimer plaques.  I think he used atomic
absorption spectroscopy (to give you an idea of the
levels present).  The EDS work I did on plaques
(1980's) showed little or no accumulation of
manganese--not much consistent evidence for aluminum

Try a PubMed search for manganese as well.  I didn't
find much in a very quick search on manganese and

Roger Moretz, Ph.D.
Dept of Toxicology
BI Pharmaceuticals.
--- "Timothy R. Wheelock"
> Hi everybody:
> Does anyone know of a stain for manganese, and if
> so, could you send me 
> the protocol?
> A researcher is looking at the role that metals play
> in Alzheimer senile 
> plaques.
> Thanks,
> Tim Wheelock
> Harvard Brain Tissue Resource Center (Brain Bank)
> McLean Hospital
> Belmont, MA
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