CD45 nuclear staining
Greetings
Histoland,
I am
perplexed. We have a squamous cell carcinoma case (poorly differentiated)
that was CK 5/6 positive, p63 nuclear positive staining and CD45 nuclear
positive staining.
The background
lymphocytes are staining membranous, but the tumor cells are staining positive
in the nucleus. I've never seen CD45 stain nuclear in the
18 + years I've been doing
this. Not even at the AFIP did see this type of staining. The tonsil
control stained like it should. Does anyone have an answer to this?
Thanks in advance.
Joe Nocito, BS, HT (ASCP)
QIHC
Histology Supervisor
Pathology Reference Lab
San Antonio, TX
jnocito@pathreflab.com
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