RE: Alzheimers stain
> HAGA is the name I have seen attached to the modified
> methenamine silver
> method for cerebral amyloid that I mentioned. I have assumed it was a
> contraction of 'Hexamine-(H)-Silver-(AG)-(A)'.
I found in Bancroft & Stevens book Theory & practise of Histological
Haga C, Yamaguchi H, Ikeda K, Kosaka K
PAM modified methenamine silver stain for senile plaques - comparison with
beta-protein immunostaining. Dementia (Japan) 1989;3:417-422.
Haga C, Ikeda K, Iwabuchi K, Akiyama H, Kondoh H, Kosaka K
Methenamine-silver staining: a simple and sensitive staining method for
senile plaques and neurofibrillary tangles.
Biotech Histochem. 1994;69(5):295-300.
so maybe Haga doesn't mean 'Hexamine-(H)-Silver-(AG)-(A)' but something else
in Japanese, I presume ;-)
BTW: What's the difference to a Sevier-Munger-stain? Can I still use it for
the detection of senile plaques? Or is it less sensitive? Maybe John
Kiernan could comment on the diagnostic differences?
Alexander Nader MD
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