ER/PR receptors


HI Histonetters
any one in the histaland can solve my problem. we use DAKO ER/PR system for estrogen progestrone receptors in the patients mostly breast specimens. our specimens are fixed in 10% bufferred formalin. the problem is that our control show good positive results but test results are variable. our pathologist says that in most of the cases if Er is negative then PR should also negative this is rare phenomena that pr is positive and er negative if any one can guide me that will be great that how i can convince my pathologist please give me some literature articles also if you have
thanks in advance

Naveeda Arshad
Pathology Department
Aga Khan university Hospital

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