Brett,

formaldehyde diffuses at about 1mm (0.78mm) per hour at room temperature.
this value, along with rates for other fixatives was determined by Medawar
in the early 40's on liver which is a pretty homogeneous tissue. rates in
other tissues i expect would be different based on composition. 

regards,
rob

-----Original Message-----
From: Connolly, Brett M
To: 'HISTONET' (E-mail)
Sent: 6/5/02 10:50 AM
Subject: NBF penetration rate

Can someone give me the tissue penetration rate of  10% NBF in mm/hr. at
room temp. 
Thanks,
Brett

Brett M. Connolly, Ph.D.
Merck Research Laboratories
Dept. of Neuroscience
WP26A-3000
PO Box 4
West Point, PA 19486
PH 215-652-2501
fax. 215-652-2075
e-mail. brett_connolly@merck.com


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