Use of Matrigel in animal models

From:"Bourassa, Patricia" <patricia_bourassa@groton.pfizer.com>

I was wondering if anyone has experience using Matrigel in animal models.
Basically, we want to subcutaneously inject matrigel containing a
chemoattractant into a mouse and measure monocyte migration.  We're pretty
sure how to introduce the protein.  My problem lies in how to isolate the
monocytes for measurement.  Any suggestions?  Can matrigel be embedded and
sectioned?

Thanks for any help!

Patti Bourassa
Pfizer PGRD
Bldg 220, x14973 or x53639



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