Nonspecific binding to mucus

From:Phil Bergin <>

Thanks to everyone who gave me advice on brittle blocks.  Now I have
another question.  I stain gastric tissue looking for macrophages and
matrix metalloproteinases, unfortunately with some of the antibodies I
get a lot of non specific binding to mucus withine the tissue, does
anyone know a good way of blocking binding to gastric mucus?


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