IHC for chronic wasting disease/bovine spong. enceph. -Reply

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From:"Catherine Robertson" <CRobertson@EM.AGR.CA>
To:marilyn.johnson@agric.gov.ab.ca, HistoNet@Pathology.swmed.edu
Date:Fri, 09 Jul 1999 15:37:10 -0400
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Hi Marilyn,

Here at NCFAD in Winnipeg we are involved in surveillance for both BSE and CWD.
We do H&Es on targeted areas as well as IHC on one or more sections from each case. We usually try to use the obex for IHC if it is available.
I was told that IHC will pick up the PrP even if there are no spongiform changes seen on the H&E section. I haven't got any references or papers in front of me right now but if you like I could dig out a few for you.

Cathy Robertson

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