Suggestions for lecture

I have been asked to give a lecture on Immunohistochemistry. My topic is: Advances in Immunohistochemistry. I want to talk about antibodies that are significant from a clinical point of view, not just the ones that confirm the diagnosis. I was thinking of things like Her2/neu and the use of Herceptin, Estrogen Receptors and Tamoxifen, etc. Some of the others that I have come up with include: Alk1, BCl2, BCl6, Etc. which are important indicators of survival. I also want to speculate a little about the future of our field. Any other suggestions would be gratefully appreciated. Thanks in advance. Tom.