RE: PCNA on guinea pig

From:"Smith, Allen"

Romer (Vertebrate Paleontology), Parsons (The Vertebrate Body), Vaughn
(Mammalogy), and McFarland (Vertebrate Life), and Walker (Functional Anatomy
of the Vertebrates) assert that guinea pigs (and other rodents) are no
closer to rabbits than they are to humans.  Rabbits are only distantly
related to other placental mammals.  Their closest relatives (aside from
pikas) are probably the hoofed animals (McFarland).

Allen A. Smith, Ph.D.
Barry University
School of Graduate Medical Sciences
    Podiatric Medicine and Surgery
Miami Shores, Florida  33161-6695

-----Original Message-----
From: Jan Shivers [mailto:shive003@umn.edu]
Sent: Tuesday, July 15, 2003 10:45 AM
To: Victoria Baker
Cc: HistoNet Server
Subject: Re: PCNA on guinea pig


I would try to stay away from using a rabbit polyclonal antibody on guinea
pigs, because they're too closely related and you may get a lot of
background (due to binding to the endogenous immunoglobulins).

Jan Shivers; Scientist
Univ. of Minn. Vet. Diag. Lab

----- Original Message -----
From: "Victoria Baker" 
To: "HistoNet Server" 
Sent: Monday, July 14, 2003 9:25 AM
Subject: PCNA on guinea pig


> Hi!
>
> Is anyone working on PCNA with guinea pigs?  I'm in a
> crunch and need to get an antibody that will react
> with guinea pig. Any info would be greatly
> appreciated.
>
> Thank you.
>
> Vikki Baker
> Institute for Cancer Prevention
> Valhalla, New York  10595
>
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