I don't agree. Acids swell tissue more than water, and it's the added
swelling that 'softens'. I have sectioned many a uterine fibroid and cone
biopsy of cervix in my time that required formic acid in addition to the
iced water routinely used to get a good section.
"Marshall Terry Dr,
Consultant To: Stephen Eyres/GB-ALNWICK/RESEARCH/SANOFI@Research
Subject: RE: Keratin
If 10% formic acid does anything it's because 10% formic acid is 90% water.
Terry L Marshall B.A.(Law), M.B.Ch.B., F.R.C.Path
Rotherham General Hospital, Yorkshire
Sent: 25 July 2002 08:42
Subject: Re: Keratin
I agree with Aidan. 10% formic acid also works well, or whatever
decalcifying agent you use.
25/07/2002 Subject: Re: Keratin
Can't beat Mollifex in my opinion.
aidan schurr b.m.l.sc
section head, histology
hutt valley district health board
++64 4 570 9173 (direct)
++64 4 570 9214 (fax)
>>> Valerie Hannen 25/07/2002 >>>
Hi fellow histonetters!!!!
Again, I have a question. Is there a "miracle" solution one can use to
soften finger and toenails for sectioning purposes? We received some really
nasty/hard ones. We tried a dilute ammonium hydroxide solution it helped a
but we hoping to find something better.
Any help you can give me would be greatly appreciated.
Parrish Medical Center
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