Apoptosis in normal lung tissue

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From:Victoria Baker <vbaker60@yahoo.com>
To:HistoNet Server <HistoNet@Pathology.swmed.edu>
Content-Type:text/plain; charset=us-ascii

Hi All!

I'm currently doing a study on apoptosis in mouse
tissue the animals are being induced and treated in 6
different groups.  Diet is also being put into the
factor - high, moderate & low.  The pathologist here
is concerned that our results are too low in the
treated/induced mice.  Our thymus control shows normal
results.  Our normal lung has maybe one or two,
sometimes none.  In all the literature I have read I
see that the results of normal lung tissue is very
low, but no one give a number.  My understanding is
that it can vary from 1-3 or even none.  Also I see
that most everyone is looking not only at In-situ
results, but at routine H&E as well.  What I'm trying
to get is a better in sight as to what others in the
field are doing to make a decision on apoptosis and
what methods they are using to come to this

Thank you for any assistance/information anyone may


Vikki Baker
American Health Foundation
Valhalla, New York

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