RE: Re - formaldehyde substitutes [Prefer] (fwd)
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From: | "J. A. Kiernan" <jkiernan@julian.uwo.ca> |
To: | Histonet <Histonet@pathology.swmed.edu> |
Reply-To: | |
Content-Type: | TEXT/PLAIN; charset=US-ASCII |
Date: Wed, 5 Jul 2000 14:31:19 -0400
From: ANATECH LTD <email@anatechltdusa.com>
Please update your files. Our website address is www.anatechltdusa.com. If
you go to ww.anatech.com you will find you are at a the website of an
engineering company.
>> We had problem with prefer-fixed tissue and immunos ... have
>> discontinued use.
>
> Can you tell us all what the problem was?
>
> Although the exact composition of Anatech's "Prefer" fixative
> is a trade secret, its active ingredient (glyoxal) and mode
> of action (aldehyde reactivity similar to formaldehyde's) are
> clearly explained in Anatech's literature (www.anatech.com)
> and in some peer-reviewed publications (e.g. Dapson, 1993
> Biotech Histochem 68:75-82). Glyoxal fixation has also been
> explained in various HistoNet messages that should be findable
> in the Archives.
>
> Any problem encountered with a glyoxal-based fixative but not
> with formaldehyde would be of general interest. So, for that
> matter, would any applications for which glyoxal turns out
> to give better fixation or antigen preservation.
Ada T. Feldman MS, HT/HTL(ASCP)
Director of Manufacturing & Technical Services
ANATECH LTD.
1020 Harts Lake Road
Battle Creek, MI 49015
800-262-8324 or 616-964-6450
Fax 616-964-8084
E-mail: email@anatechltdusa.com
http://www.anatechltdusa.com
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