I would seem that some of our wonderful manufacturers could produce and
offer such an item.   Or....if I am behind the times and it is already out
there, let me know....I would be interested.

> ----------
> From: 	Jeff Silverman[SMTP:peptolab@hamptons.com]
> Sent: 	Friday, January 22, 1999 1:50 PM
> To: 	brandon; histonet@Pathology.swmed.edu
> Subject: 	Re: Parrafin core samples
>
> Dr Juan Rosai of Memorial Sloan Kettering Cancer Center showed us at the
> Society for Applied Immunohistochemistry a type of home- made (I believe)
> trephine like punch approx 5-6mm in inside diameter that they used to
> create these multi-tissue blocks.  All you need is a cylindrical or
> tubular
> piece of metal whose edge can be sharpened, not necessarily razor sharp,
> and a thinner piece of metal (or wood or whatever) that fits inside this
> tube to push the core of paraffin embedded tissue out of the trephine. To
> obtain the core, you twist and press the trephine into the part of the
> block that you want and it removes a core.  These cores can then be
> labelled and saved and are embedded together once you have accumulated all
> of the samples that you wish to include in your multitissue block.  Keep a
> record and embed them in straight rows and you have a wonderful tool to
> evaluate new antibodies. They used 40 tissues in their tumor blocks, ten
> columns, 4 rows.
>
> Jeff Silverman Southampton NY
>
>
> ----------
> > From: brandon <schanbacher.2@osu.edu>
> > To: histonet@pathology.swmed.edu
> > Subject: Parrafin core samples
> > Date: Friday, January 22, 1999 4:00 PM
> >
> > I've recently heard of a device which takes core punches out of a
> paraffin
> > blocks and  re-embeds them into a single block, resulting in a paraffin
> > block containing multiple samples.  Unfortunately, this was only
> mentioned
> > in passing and I have no other information about it.  If anyone knows
> > anything about this type of device, particularly any vendors, etc..., I
> > would appreciate it.  Private reply is fine.
> >
> > Thanks in advance,
> >
> > Brandon Schanbacher
> > schanbacher.2@osu.edu
> > Ohio State University
> > Division of Pharmacology
> >
>