[Histonet] Nuclear Staining on Prostate Biopsies

From:"Laurie Elmgren"

I would like to optimize the quality of our stain.  We process office
biopsies, a good variety of tissue types.

The stain is consistently very good. There are three colors of Eosin,
and good nuclear detail on most tissue types, except for the prostate

The nuclei are stained dark and are "flat" having no depth.

I am thinking that it is not the fixation, because our Monday specimens
that are held over a full day are no different than those throughout the

Any suggestions before I start reprogramming the stainer?


Laurie Elmgren

Histology Supervisor

Sunrise Medical Labs

240 Motor Pkwy

Hauppauge, NY 11788



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