[Histonet] Re: Blue Nevus Disease-Help?
Scheherazade Humphrey asks about possible immunohistochemical staining of a
Blue nevus - an uncommon but not rare benign variant of pigmented nevus -
should mark for S100, but it's nearly always an H & E diagnosis. The usual blue
nevus isn't a disease, just an isolated skin lesion. Bundles of heavily
pigmented spindly melanocytes are present in the dermis but there are usually no
nevus cell nests in the basal layer of the epidermis, so the pigment looks
bluish when you look at the nevus "on the hoof".
Scheherazade - what a name - since my wife's a storyteller - I hear
Scheherazade's narrator theme, first stated (I think) by the violin - in Nikolai
Rimsky-Korsakoff's orchestral suite of that name - one of my parents' favorite
classical pieces, on those fragile old 78 rpm shellac records back when I was a kid
in the 1940's -
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