RE: [Histonet] Number of GI biopsy sections on a slide for pediatrichospitals.

From:"Julia Dahl"


Hello Annette -

>From the perspective of a gastrointestinal pathologist, the more sections 
that you can provide for review, the better for the patient - particularly 
in pediatric patients.

At the University of Washington Gastrointestinal Pathology Laboratory, each 
block would have two complete ribbons of tissue per slide, two slides per 
block.  This would result in about 60 to 120 sections per block for the 
pathologist to review.  The blocks were trimmed very close to the tissue and 
standard 4 micron sections were ribboned, with ribbons placed about 5 mm 
from one another  on the slides.

While this is "overkill" for many standard adult GI cases, such as routine 
tubular adenomas in adults, the degree of accuracy in inflammatory disorders 
is impacted substantially by providing additional sections for review.

If you would like to contact me directly to discuss, I would be happy to 
provide some literature about diagnostic accuracy and biopsy handling.

Julia Dahl, M.D.
Founder, Principal Investigator
Mosaic Gastrointestinal Pathology Research Consortium
Memphis, TN

>From: "Foshey, Annette" 
>To: 
>Subject: [Histonet] Number of GI biopsy sections on a slide for 
>pediatrichospitals.
>Date: Wed, 4 Jan 2006 15:50:35 -0600
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>
>I am inquiring what the "standard" is for the number of GI biopsy
>sections that are routinely put on slides for review. We currently cut
>two slides with two levels on each slide.  The total number of sections
>is between 6-8 sections on each slide.
>
>Thanks,
>Annette Foshey, HT
>Team Leader in Histology
>Children's Hospital of Wisconsin
>
>
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