laser-activated dyes

From:David Van Reyk

Happy 20th January to everyone!

We are involved in a study examining the efficacy of laser photo-coagulation of the retina in a rat study. We would like to be able to pinpoint in histological sections sites of laser burn (morphological changes aren't that clear cut). One thought is to introduce a photo-activated compound into the retina which would form a stable reaction product (i.e. stable enough to survive storage and tissue processing). Anyone have any ideas? Some possibilities would be (i) a product that might form an insoluble precipitate or (ii) form an adduct with cell components.

Dr David van Reyk,
Dept Health Sciences,University of Technology,Sydney, 
PO Box 123, Broadway, NSW 2007, AUSTRALIA
Ph 61-2-9514-2221 FAX 61-2-9514-2228 

UTS CRICOS Provider Code:  00099F

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