Her 2 and fixation

From:"Marshall Terry Dr, Consultant Histopathologist"

We have just noticed from Dako that:

"Her 2 positivity is "compromised by other than phosphate buffered formalin fixation" "

Since Her 2 seems to be the latest craze, this is of some concern.
Has anyone got any further details, or a rebuttal of this, particularly in relation to zinc fixation?



Terry L Marshall B.A.(Law), M.B.Ch.B., F.R.C.Path
Consultant Histopathologist
Rotherham General Hospital, Yorkshire
terry.marshall@rothgen.nhs.uk



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