PGA and PLLA processing
John Bobst ask, "Does anyone know of any adverse reactions or cautions to
processing either PGA or PLLA?".
PGA or PLLA are both absorbable polymers and can be affected by many
factors such as heat, light, liquids, etc.. However, I would recommend
that you take some samples of each material and leave in the acetone and
Spurr's for an allotted time and see what happens. Our pilot studies
indicated that both materials will begin to degrade in acetone and certain
resins ( we did not test Spurr's). Also, these materials can be sensitive
to heat (at what temp does Spurr's polymerize?). You might want to consider
a light curing resin for your embedding medium.
You also stated that you were "fixing" the bone in 70% ethanol. Is there
any reason you are not using 10% formalin? In my humble opinion, trying to
fix a sheep spine in 70% ethanol is a disaster waiting to happen ( been
there, done that!). However, 70 % ethanol works well for long term
"storage" of well-fixed bones.
Hope you find this useful and please feel free to contact me for further
info if needed,
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