immunohistochemical staining on tissues fixed with recycled formalin

From:Vinnie Della Speranza

Has anyone seen aberrant immunohistochemical staining that might be attributable to fixing tissues with recycled formalin ?
We have been using a formalin recycler on demo. each run has been assayed for concentration, adjusted if necessary and re-buffered.  The recycled product appears morphologically to be performing as expected but the question of impact on immuno-staining has been raised.
 
thank you for your views on this.
 

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