Richard,
No I have not, but I am not surprised. Years ago, I
found that cases of prostatic carcinoma showing
squamoid metaplasia, following therapy, failed to
stain with Prostate specific antigen nor Prostatic
acid phosphatase. I did wonder afterwards whether high
MW keratins could be demonstrated in these cells.

Regards,
Tony 


--- Richard Cartun  wrote: > Has
anyone noticed diffuse cytoplasmic staining for
> high molecular weight cytokeratin (clone 34BetaE12)
> in prostatic glands from patients who have received
> radiation therapy for prostate CA?  Thanks!
> 
> RWC
> 
>  

=====
Tony Henwood JP BAppSc GradDipSysAnaly CT(ASC)
Laboratory Manager
Histopathology Department
The Childrens Hospital at Westmead
Locked Bag 4001
WESTMEAD, 2145
AUSTRALIA

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