microtissue array - a new method: the multiblock system

From:"Dr. Reinhard von Wasielewski" <Wasielewski.Reinhard.von@MH-Hannover.de>

The multiblock GbR (Germany) offers now a free booklet of "how to use 
the multiblock system" in English ! It will be sent to you as a PDF 
version on request: > wasielewski.reinhard.von@mh-hannover.de < (or 
via: www.multiblock.de)

The multiblock-system is different from the beecher system, i.e. you 
punsh your tissue cores yourself of the interested area of your 
archival block by yourself (1.5 mm in diameter) and send them to 
multiblock. All you need in included in the kit you have to 
buy from multiblock GbR. In few month, we will offer our service 
directly from US. At the moment,however, the inventors (patent 
pending) will do it by themselves in Germany. 
The multiblock you receive (containing your own tissues) can 
be cut like any standard paraffin block, you need no special 
equipment. Depending on the thickness of the tissue cores brought 
into the multiblock, up to 150 slides can be achieved on a routine 
microtome. Therefore, the technique is especially interesting for 
studying several markers on the same tissues. No tape system ! We 
have used this multiblock system in a nationwide immuno-trial this 
spring in Germany. We sent out 6 slides of a multiblock containing 30 
tissue cores to 172 laboratories (6x30x172 =approx. 31.000 cores). 
They were sent back to us after staining for ER, MIB1, Keratin, 
...(i.e. including heat retrieval methods). Less than 0.4% of the 
31000 cores were lost due to adhesion problems (in 172 different 
laboratories !!!), which is a very low number that corresponds well 
to loss on standard slides (or even below).  The multiblock system is 
also appropriate for In-Situ-hybridization, we have investigated more 
than 2000 cases up to now in 34 multiblocks with no real problems. 

Introductory offer: One multiblock with up to 60 of your tissue cores 
$ 450 (add your package and postage to sent the tissue cores to us, 
add banking transfer costs, at the moment only prepaid orders will be 
Once tried, you will never want to miss this upspeeding technology !
multiblock Dres von Wasielewski Mengel Lilischkis GbR, Isernhagen, 
Reinhard von Wasielewski, MD

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