-----Original Message-----
From: John Spair <jspair@multicare.com>
To: histonet@pathology.swmed.edu <histonet@pathology.swmed.edu>
Date: Thursday, February 25, 1999 10:09 AM
Subject: Fw: Formalin/Alcohol Question


>
>Histonetters:
>
>Some people in pathology say they have experienced a loss of
>immunoreactivity when tissues are fixed in formol-alcohol.  One lab for
>instance that we have referred out ICC, won't do ICC on any tissue fixed in
>formol-alcohol.  Another lab says they have no trouble whatsover.  Recently
>our pathologists started fixing our breast and colon cases in
formol-alcohol
>and since most of these breast cases get a "breast battery" panel done on
>them, such as ER/PR, etc. - a concern has arisen between our pathology
group
>about the use of formol-alcohol.
>
>I'm curious to find out other histonetters opinions, or experiences before
>making a final decision and telling our pathology group that we cannot use
>it any longer.  Thank you.
>
>