We fix ours in zinc-formalin and do not have this problem.Toni-----Original Message-----From: histonet-bounces@lists.utsouthwestern.edu[mailto:histonet-bounces@lists.utsouthwestern.edu]On Behalf Of Metzger,KennethSent: Friday, February 29, 2008 11:00 AMTo: histonet@lists.utsouthwestern.eduSubject: [Histonet] Bone Marrow IssuesWe are seeing an artifact that causes loss of nuclear detail, particularly in erythroid cells, giving an appearance of being blown up with no nuclear detail. It is worse in decaled cores. This appears when we fix the cores and clot in formalin. We were using Z-5 and did not have this issue. My Pathologist wants to stick to formalin. None of our other tissue has this issue. Has anyone had this happen? Any help would be appreciated.KenKen Metzger HTL(ASCP)Histology SupervisorARUP Laboratories500 Chipeta waySalt Lake City, UT 84108801.583.2787 ext 3101- ------------------------------------------------------------------The information transmitted by this e-mail and any includedattachments are from ARUP Laboratories and are intended only for therecipient. The information contained in this message is confidentialand may constitute inside or non-public information underinternational, federal, or state securities laws, or protected healthinformation and is intended only for the use of the recipient.Unauthorized forwarding, printing, copying, distributing, or use ofsuch information is strictly prohibited and may be unlawful. If youare not the intended recipient, please promptly delete this e-mailand notify the sender of the delivery error or you may call ARUPLaboratories Compliance Hot Line in Salt Lake City, Utah USA at (+1(800) 522-2787 ext. 2100_______________________________________________Histonet mailing listHistonet@lists.utsouthwestern.eduhttp://lists.utsouthwestern.edu/mailman/listinfo/histonetCONFIDENTIALITY NOTICE
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