RE: [Histonet] IL1 KO mouse and cytokines in neurons

From:"Jacqui Detmar"

Hi Victor.  

IL-1alpha was knocked out by Iwakura's group in 1998 (see Horai et al.,
1998).  IL-1beta was knocked out by David Chaplin's group (see Shornick
et al., 1996) and Lex Van der Ploeg's group (see Zheng et al., 1995).
Have you tried depleting the antibody with the peptide immunogen?  Is
this even possible for these antibodies?  Just a thought.  Good luck

Jacqui Detmar, Post-doctoral Fellow
Samuel Lunenfeld Research Institute, room 876
Mount Sinai Hospital
600 University Avenue
Toronto, ON, Canada
M5G 1X5

phone:   416-586-4800 x2451/x2290
fax:        416-586-8588


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