the hypoxia story: you give the patient iv
pimonidazole (the hypoxia marker). after some hours
you take the biopsy and you add the antibody that
recognizes the pimonizadole bound. 
if there is no pimonidazole there is no reason to
proceed with the antibody.
these chaps have a brain biopsy material and they want
to see if there is hypoxia. i am afraid is not
possible without the soministration of pmn before the
biopsy.
That's from a Great Reseacher who I am working with

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