We are having a transient issue with renal biopsies washing off coated slides.  They are all processed in B5 from VWR and diluted with formalin from Fisher and a small amount of safranin to color the tissue.  Tissue from yesterday appeared shrunken and brittle - but biopsies from previous days were fine using above reagents from the same lot number.  Any experience or thoughts regarding this issue would be appreciated.   
Thanks,  Tracey

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