Re: [Histonet] Formalin pigment

From:John Kiernan

Formalin pigment is formed by the action of acid
(pH <5.6) or alkali (pH >8) on haemoglobin. According 
to Lillie's big book (p. 488-489) similar pigment occurs 
around sites of haemorrhage in the gastric mucosa; it's
then called HCl pigment. Malaria pigment is also
closely similar. Lillie cites his own work in the field,
which was published as 3 papers in 1947.
-- 
-------------------------------
John A. Kiernan
Department of Anatomy and Cell Biology
The University of Western Ontario
London,   Canada   N6A 5C1
   kiernan[AT]uwo.ca
   http://publish.uwo.ca/~jkiernan/
   http://instruct.uwo.ca/anatomy/530/index.htm
_______________________________
"Bruijntjes, J.P." wrote:
> 
> Is there anyone who can tell me what other reason could cause the
> formation of formalin pigment except a too acidic formalin?
> 
> 
> 
> Joost Bruijntjes
> 
> TNO Nutrition and Food research
> 
> Zeist
> 
> The Netherlands
> 
> 
> 
> This e-mail and its contents are subject to the DISCLAIMER at http://www.tno.nl/disclaimer/email.html
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