RE: Estrogen and Progesterone Receptors on DCIS

From:"Peter Burke, MD"

I have heard this issue raised before and what I have learned is (1) high
grade DCIS has been shown to be almost always negative for ER & PR receptors
and (2) no one is quite sure what to do with the results of ER PR
determinations in DCIS. I am not aware of any change in the clinical
management of the patient with DCIS dependent on ER & PR status.

Peter R. Burke, MD
Northwestern Medical Center
Saint Albans, Vermont

-----Original Message-----
From: Bell, Lynne [] 
Sent: Wednesday, February 05, 2003 10:19 AM
To: ''
Subject: Estrogen and Progesterone Receptors on DCIS

One of our pathologists just informed me that our oncologists would like us
to do ER and PR's on all cases with ductal carcinoma insitu.  Is anyone else
doing this?  As about 30% of the breast tissue we receive has DCIS, this is
going to significantly impact our workload, which leads me to my next
question.  Does anyone have some ideas for a small, reliable immunostainer?

Thanks so much for you help,

Lynne Bell, HT (ASCP)
Lead Histotechnician
Central Vermont Hospital
Barre, VT

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