From:David Grehan <>

Does anyone have any neat suggestions concerning the demonstration of
Reed Sternberg cells when they are embedded in an intense inflammatory
background . We get many cases of Hodgkins disease in which the
infalmmatory background renders it difficult to be sure of CD15 positve
RS cells . We also stain for  RS  cells using CD30 which will not light
up inflammatory cells but is also nonspecific for this cell type. Does
anyone double immunostain for example?
Just curious.
David Grehan

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