Formaldehyde, Authority, and Re: FLT-1/FLK-1 ISH
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From: | "J. A. Kiernan" <jkiernan@julian.uwo.ca> |
To: | AndreaH@imclone.com |
Reply-To: | |
Content-Type: | TEXT/PLAIN; charset=US-ASCII |
On Tue, 15 Feb 2000 AndreaH@imclone.com wrote:
> I thought there was little or no difference between 4% paraformaldehyde and
> 10% neutral buffered formalin. Will a chemist step in and resolve my
> confusion??
I'm not a chemist, but know enough to assure you that you
are entirely correct in your thoughts about formaldehyde.
All this has been the subject of dozens of HistoNet
communications. Now the archives are again available
on the web, there's no point re-quoting the textbooks
yet another time.
The Archives are very good - well indexed etc - but
we must remember that this informal exchange of
questions and answers is not the font of eternal
wisdom. The only reliable sources of information are
peer-reviewed journals and textbooks (which cite the
journals, and also are quite severely vetted by their
publishers before being taken on as commercial risks).
Every lab doing histology should have a shelf full of
big textbooks (10 X $100 = $1000) and two or three
journals (@ $100 to 200 per year each: Max. $600 per
year). Total expenditure is $1000 statim and a few
hundred a year thereafter. This is well below 1% of
the salary of some worthless senior administrator ...
(Perhaps I'd better say no more, having made the point.)
John A. Kiernan,
Department of Anatomy & Cell Biology,
The University of Western Ontario,
LONDON, Canada N6A 5C1
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