multi drug resistance protein

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From:David Grehan <>
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Hi histolanders,
I am trying to locate a good antibody to Multi Drug Resistance Protein
that works well on paraffin processed neuroblastoma tumours. Does anyone
have any experience using these antibodies with this tumour or any other
tumour type. I have tried a monoclonal antibody to MRP (QCRL1) from ID
Labs at a 1:20 dilution following pressure cooker AR without much
success. The MRP gene is over expressed in MYCN amplified  neuroblastoma
tumours .
Secondly does anyone routinely detect the amplified MYCN gene copy in
paraffin sections and where do you obtain the probe.


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