Re: sentinel node

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From:Bruce Schainker <>

Regarding Adriana's question about which cytokeratin to use on 
sentinel nodes:  Look at the abstract (#1321) by Linden and Zarbo in 
Modern Pathology 2000; 13:224A.  They compared AE 1/AE3, CAM 5.2 and a 
CK cocktail of 7 anti-CK Abs.  They found the CK cocktail to be the 
mosts sensitive Ab, staining more tumor cells with increased 

Bruce A. Schainker, M.D.
Director, Department of Pathology
Holy Name Hospital
Teaneck, NJ

------------------ Reply Separator --------------------
Originally From: "Turriago, Adriana" <>
Subject: sentinel node
Date: 02/07/2000 01:41pm

Hi all!

Could anyone tell me which Ab(s) is (are) most commonly used in 
node staining?  Which one is better and gives the least amount of
background?  Is there a great difference between AE1/AE3 and CAM 5.2?

Thanks for your help


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