RE: (no subject)

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From:"Saby, Joseph" <Joseph.Saby@wl.com> (by way of histonet)
To:histonet@histosearch.com
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Lee-

When handling old world monkeys, you should be wearing a suit that covers
all your clothes, gloves (latex or equivalent to cover your hands, stainless
steel mesh as well if you are handling the monkeys for dosing and are at
risk for a bite), paper booties to cover your shoes and a bonnet to cover
your hair.  Your should be wearing a mask/respirator capable or filtering
vapors (Scott's 2200 or equivalent).  Your eyes should be covered with
goggles or a face shield that will protect your eyes not only from a direct
or lateral spray but also from something spraying on your forehead and
dripping down into your eyes.

The risk of transmission is through being exposed to bodily fluids (blood,
saliva, etc.) which can come in contact with open areas of your body (cuts,
needle pokes, eyes, nostrils, mouth, etc.).  If you are wearing the proper
protective gear and following proper handling protocols, this risk should be
minimal.  But I also realize that handling these monkeys is tricky, as they
are smart and can be aggressive.

I do not know for sure, but believe the drugs used to treat exposure would
primarily be in the class of Acylcovir or Famvir, both used for the
treatment of shingles or other herpes outbreaks.  I have no idea of the
effect of these during pregnancy.  There are certainly other drugs which
could be used, but I am not familiar with them.  I only know of the two
listed from treatments I have had for a very nasty case of shingles.

I hope this helps.

Joe

Joseph A. Saby, BA HT(ASCP)
Diagnostic Pathology, Pathology & Experimental Toxicology
Parke-Davis/Int. Pharm. Res. Div. Warner-Lambert
Ann Arbor, MI 48105
Phone: (734) 622-3631
Fax:     (734) 622-5718
e-mail:  Joseph.Saby@wl.com


-----Original Message-----
From: Moonli911@aol.com [mailto:Moonli911@aol.com]
Sent: Saturday, December 04, 1999 4:18 PM
To: histonet@pathology.swmed.edu
Subject: (no subject)


Do you have
any literature on the risk of transmission of Herpes B virus to nursing
female handlers of rhesus monkeys/tissues/products? The medication that you
are put on to prevent death in the event that you are infected. I would like

to learn more about this information.
Thank you in advance for a speedy reply.
lee




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