Hi Guys,

We have recently purchased the BioCare Decloaker and have been impressed with our improved antigen retrieval results.  Especially for antigens such as Thyroid Transcription Factor 1 and Cytokeratin cocktail 5 & 6.  However,  it has given us some problems with spiking of high temperatures and subsequent destruction of tissue sections.  Also nuclear detail seems to be reduced when using this instrument.

Has anyone else out there had problems like this and can we expect anything else?

Sue Sturrock
Austin Health
Melbourne, Australia

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